Summer House

PARIS (AFP) — The drug buprenorphine is twice as effective as a rival treatment called naltrexone in helping heroin patients stay off the narcotic, a trial published in The Lancet on Friday said.

The two drugs, along with a dummy pill called a placebo, were tested for 22 months among 126 patients in Malaysia who had emerged from a detoxification and counselling programme, it said.

Buprenorphine, which is marketed as Temgesic or Buprenex, was twice as effective as naltrexone (branded as Revia, Depade or Vivitrol) and the placebo in terms of days of abstinence from heroin and a full-fledged relapse to the narcotic.

Indeed, buprenorphine proved to be so superior that the trial was halted early, as it would have been unethical to continue it to its scheduled end.

The study, led by Yale University’s Richard Schottenfeld, gives support for placing buprenorphine alongside methadone, and both of them over naltrexone, as pharmacological treatments for helping addicts stay off heroin.

The three drugs belong to a class called opioid antagonists.

These treatments are increasingly used to help ease heroin dependence but remain prohibited in some countries, amid suspicions that they are liable to be abused or simply substitute one addiction for another.

The study is important because it gives the first assessment of the relative effectiveness of two of the opioid antagonists.

Heroin and other illicit opiates were once a problem mainly confined to developed countries, but in the past few decades have spread to developing economies and nations of the former Soviet bloc.

China, India, Indonesia, Iran, Malaysia, Pakistan and Russia are among the countries where expansion of heroin use has risen fastest, according to a 2004 World Health Organisation (WHO) paper.

Sun Sentinel — South Florida is tops in all the wrong things again, this time in prescription drug overdose deaths, with Palm Beach County leading the state in fatal methadone overdoses last year, and Broward ranking second in deaths involving the anti-anxiety drug Xanax and third in oxycodone fatalities.

No one knows why South Florida owns this tragic distinction, but one thing is clear: It proves why crackdowns on doctor shopping and unscrupulously run "pill mills" are so essential. And why they deserve an even higher ranking on the law enforcement priority list.

Drug addiction is not a victimless problem. Even if it’s not your loved one who’s hopelessly hooked, your safety may be affected because addicts often turn to crimes like burglary or robbery to feed their habit.

So combating addiction, and reducing the incidence of overdoses, is a societal, not just a personal, responsibility.

Fox News — A warning from the Colorado Springs Police Department. Detectives with Metro Vice Narcotics said more and more teens are throwing "pharm parties," or get-togethers where young adults abuse prescription drugs.

Detectives said most teens get the medications from their parents and grandparents medicine cabinets. They said from there, the prescription drugs are then taken to parties and shared with the group.

Over the past few months, police said a handful of teenagers have overdosed on the drugs. They said some of the more popular pills include Xanax, Valium, Percoset, Oxycontin, Vikatin and Adderall to name a few.

It is called "trail mix," or a bowl filled with prescription drugs free for the taking. Detectives with the Colorado Springs Police Department said "trail mix" is the new party favor at many teen get-togethers.

"Then the kids just take turns taking a pill of their choice to see if it affects them and to see if they like it or not," an undercover officer with Metro VNI said.

Detectives with VNI said they have seen youth ages 12 to 22 abuse the drugs.

"I have had reports of pills being taken from grandma and grandpas when they go visit, aunts and uncles, friends going over to another kids house and taking from that medicine cabinet," a VNI Detective said.

The most popular pills detectives said are schedule II medications, or drugs that are highly addictive.

"Cocaine and meth are schedule II, Adderall, Oxycontin and Percosit are all schedule II as well, so they have the same abuse and addiction potential," a VNI Detective said.

Police said the internet has only made things worse by spreading information.

"They did an interview with a youth who overdosed, and the way he chose what medication to take was if it said ‘do not use with alcohol,’ that meant to him it was a great drug to use," a VNI Detective said.

They said many teens think prescription drugs are safe because they are prescribed by a doctor.

"Definitely, we have seen overdoses," a VNI Detective said.

To keep your kids safe, police said treat your pills like a gun, lock them up and put them away.

Detectives with VNI said prescription drug abuse is a nationwide problem that also affects millions of adults. If you or someone you know is abusing prescription pills log onto the website below for help.

(CNN) – Drug enforcement authorities are concerned about the use of potent new drug cocktails that combines prescription medicine and street drugs.

The new type of abuse, which drug experts call "pharmacological roulette," is being noticed among high school and college students, and is potentially deadly. Police in Hartford, Connecticut believe the death of a Trinity College student may have involved mixing various prescription medicines with other types of drugs.

Although experts don’t know if the pattern of abuse is growing, one survey at the University of Wisconsin found one in five students had tried illicit prescription drugs.

Both drug experts and recovering teen-agers at the Phoenix House Treatment Center in Lake Ronkonoma, New York, tell CNN’S Frank Buckley that obtaining the drugs is as easy as going to the drugstore, buying from sellers on the street or ordering from the Internet.

(CNN) — The transitional year between child and teenager is crucial in fighting teen drug use, according to a new survey.

The research by the Columbia University’s National Center on Addiction and Substance Abuse found age 12 to 13 to be a time when children are increasingly exposed to drugs and often moving away from the control and influence of their parents.

"In no other year do teens’ perceptions and attitudes shift so markedly," the center said.

The survey found a 13-year-old is three times more likely than a 12-year-old to know how to buy drugs. It also found about twice as many 13-year-olds do not have adult supervision at home after school.

"America’s children have been crying out for help and not enough people are listening," said the center’s president, Joseph A. Califano Jr.

The annual survey of 1,000 teen-agers, 824 teachers and 822 principals found for the fourth year, teens believed drugs were their most pressing problem. In all, 39 percent of 17-year-olds said they drank alcohol, 23 percent said they smoked in the last 30 days, and 41 percent said they have smoked marijuana.

Teenagers who used one substance such as alcohol were more likely to use another such as marijuana, and marijuana uses were more likely to drink.

The survey documented a wide gap between the students and principals in perceived drug use in their schools. More than half of teen-agers and 41 percent of teachers said the drug problem at their schools is getting worse, but just 15 percent of principals saw an increasing problem.

Eighteen percent of principals, compared with 78 percent of teen students, said their schools were not drug-free.

"Principals make monkeys of themselves as they reveal their see no evil, hear no evil, speak no evil posture," said Califano, a former secretary of Health, Education and Welfare in the Carter administration.

The survey did find some hopeful statistics. It reported teen-agers who attend religious services are less likely to smoke cigarettes or marijuana or spend time with those who do.

It also found teen-agers who have never smoked marijuana are more likely to heed their parent’s opinions.

WASHINGTON (AP) — Marijuana potency increased last year to the highest level in more than 30 years, posing greater health risks to people who may view the drug as harmless, according to a report released Thursday by the White House.

The latest analysis from the University of Mississippi’s Potency Monitoring Project tracked the average amount of THC, the psychoactive ingredient in marijuana, in samples seized by law enforcement agencies from 1975 through 2007. It found that the average amount of THC reached 9.6 percent in 2007, compared with 8.75 percent the previous year.

The 9.6 percent level represents more than a doubling of marijuana potency since 1983, when it averaged just under 4 percent.

"Today’s report makes it more important than ever that we get past outdated, anachronistic views of marijuana," said John Walters, director of the White House Office of National Drug Control Policy. He cited baby boomer parents who might have misguided notions that the drug contains the weaker potency levels of the 1970s.

"Marijuana potency has grown steeply over the past decade, with serious implications in particular for young people," Walters said. He cited the risk of psychological, cognitive and respiratory problems, and the potential for users to become dependent on drugs such as cocaine and heroin.

While the drug’s potency may be rising, marijuana users generally adjust to the level of potency and smoke it accordingly, said Dr. Mitch Earleywine, who teaches psychology at the State University of New York in Albany and serves as an adviser for marijuana advocacy groups. "Stronger cannabis leads to less inhaled smoke," he said.

The White House office attributed the increases in marijuana potency to sophisticated growing techniques that drug traffickers are using at sites in the United States and Canada.

A report from the office last month found that a teenager who has been depressed in the past year was more than twice as likely to have used marijuana than teenagers who have not reported being depressed — 25 percent compared with 12 percent. The study said marijuana use increased the risk of developing mental disorders by 40 percent.

"The increases in marijuana potency are of concern since they increase the likelihood of acute toxicity, including mental impairment," said Dr. Nora Volkow, director of the National Institute on Drug Abuse, which funded the University of Mississippi study.

"Particularly worrisome is the possibility that the more potent THC might be more effective at triggering the changes in the brain that can lead to addiction," Volkow said.

But there’s no data showing that a higher potency in marijuana leads to more addiction, Earleywine said, and marijuana’s withdrawal symptoms are mild at best. "Mild irritability, craving for marijuana and decreased appetite — I mean those are laughable when you talk about withdrawal from a drug. Caffeine is worse."

The project analyzed data on 62,797 cannabis samples, 1,302 hashish samples, and 468 hash oil samples obtained primarily from seizures by law enforcement agencies in 48 states since 1975.