Summer House

ORLANDO, Fla. — When Bryan stopped taking drugs six months ago, he got through the worst of his heroin withdrawal in a week. It was Xanax that tortured him for a full month.

He longed for the "benzos," slang for benzodiazepines, the class of drugs that includes Xanax, to take the edge off his skittishness, sleeplessness and anxiety.

Although Bryan used a variety of drugs for about 12 years, the Orlando man found Xanax one of the hardest to let go.

"Once you get fixated on downers like that, you don’t stop easily," said Bryan, 29, who asked not to be identified by last name to protect his business. "Especially if you’re a high-strung individual, it just gives you an extremely relaxing feeling. It’s slows down your thought process; you take everything in stride."

Xanax is a prescription medication used to treat anxiety. But it also is a highly abused, easily addictive tranquilizer and the focus of a fraudulent prescription drug charge against Gov. Jeb Bush’s 24-year-old daughter, Noelle.

If convicted, officials said, Noelle Bush likely would be given probation as a first-time offender.

She will not be required to appear in court personally until after formal criminal charges are filed, a process that generally takes four to six weeks, Leon County Assistant State Attorney Owen McCaul said.

Xanax and other prescription drugs are becoming increasingly popular with younger people, according to the National Institute on Drug Abuse. A government survey in 2000 found that about 5 million Americans have abused Xanax or a similar anti-anxiety drug at some point.

" It ’s basically the modern-day version of a Quaalude,  the mother’s little helper," said Lui Delgado, a certified addictions professional and executive director of Quest Counseling Centre in Altamonte Springs. " It ’s very common with young people, and it ’s very easy to find."

Xanax is the brand name for alprazolam, a drug developed at least 20 years ago as an alternative to Valium, a widely prescribed sedative that was considered too easily addictive.

But both drugs can create powerful addictions, and some say Xanax is worse than Valium.

"Xanax, in particular, is abused because it has a fairly quick uptake into the system, and many people get a buzz from it, " said Dr. Herndon Harding, medical director of Florida Hospital ’s Center for Behavioral Health.

Xanax works by depressing the central nervous system, enhancing the effects of a chemical in the brain that slows down the firing of neurons and reduces brain activity.

Bryan said taking Xanax felt like having a few drinks, minus the dizziness. He could get 100 pills for about $200, but the drug sells for up to $5 a pill on the street.

Most prescriptions call for no more than 2 mg of Xanax total a day. Because he had built up a tolerance, Bryan needed about 10 mg to get the desired effect.

They don’t know each other, but they have much in common:

They’re both from small towns — Masure from St. Johnsbury, Vt., Payne from Hanover, Va. They used to steal beers from their dads before branching out into a variety of drugs.

They have been "clean" for three years, thanks in part to several 12-step program meetings each week. And they’re both preaching what they practice by working for organizations that offer support to people and families struggling with addiction.

Their stories touch upon themes made clear recently by scientists searching for answers about the genesis and treatment of addiction. The questions have plagued researchers for decades, but only in the past several years have they had the tools — such as technology that provides a real-time view of brain function — to unravel them.

The 2004 National Survey on Drug Use and Health found that of Americans 12 and older, nearly 8.4 million were addicted to alcohol and nearly 5 million were addicted to other drugs. About 1.4 million were addicted to both, according to the survey by the federal Substance Abuse and Mental Health Services Administration.

Thanks to advances in neurobiology, "we have enormous knowledge now of what’s going on" in addicts’ brains, says George Koob, professor of molecular integrative neuroscience at the Scripps Research Institute in La Jolla, Calif. Koob, who calls himself an "irrepressible optimist," says he is hopeful that new insights into the mechanisms of addiction will lead to new treatments and reduced suffering.

They might debate the terms used to describe addiction, but top scientists in the field pretty much agree on what it is.

"The inability to stop is the essence of what addiction is," says Nora Volkow, director of the National Institute of Drug Abuse, part of the National Institutes of Health. As Payne, 27, puts it, "my favorite drug was more and all."

That’s not to say that people who can’t make it through the day without latte grandes or Ghirardelli chocolate are addicts, says Volkow, a self-professed "chocoholic" who has pioneered brain-imaging studies of addiction. Caffeine does activate some of the same brain circuits as the drugs of addiction, but only very mildly, she says. Caffeine can be habit-forming, but Starbucks devotees won’t risk jail time or divorce to feed their habit.

Nor is addiction the same as dependence, although the American Psychiatric Association’s diagnostic manual says it is, says Volkow, who’s pushing to drop that wording. "Addiction is much harder to treat. Everybody given an opiate (such as morphine) will become physically dependent, but not everybody will become an addict."

They don’t know each other, but they have much in common:

They’re both from small towns — Masure from St. Johnsbury, Vt., Payne from Hanover, Va. They used to steal beers from their dads before branching out into a variety of drugs.

They have been "clean" for three years, thanks in part to several 12-step program meetings each week. And they’re both preaching what they practice by working for organizations that offer support to people and families struggling with addiction.

Their stories touch upon themes made clear recently by scientists searching for answers about the genesis and treatment of addiction. The questions have plagued researchers for decades, but only in the past several years have they had the tools — such as technology that provides a real-time view of brain function — to unravel them.

The 2004 National Survey on Drug Use and Health found that of Americans 12 and older, nearly 8.4 million were addicted to alcohol and nearly 5 million were addicted to other drugs. About 1.4 million were addicted to both, according to the survey by the federal Substance Abuse and Mental Health Services Administration.

Thanks to advances in neurobiology, "we have enormous knowledge now of what’s going on" in addicts’ brains, says George Koob, professor of molecular integrative neuroscience at the Scripps Research Institute in La Jolla, Calif. Koob, who calls himself an "irrepressible optimist," says he is hopeful that new insights into the mechanisms of addiction will lead to new treatments and reduced suffering.

USA Today — They might debate the terms used to describe addiction, but top scientists in the field pretty much agree on what it is.

"The inability to stop is the essence of what addiction is," says Nora Volkow, director of the National Institute of Drug Abuse, part of the National Institutes of Health. As Payne, 27, puts it, "my favorite drug was more and all."

That’s not to say that people who can’t make it through the day without latte grandes or Ghirardelli chocolate are addicts, says Volkow, a self-professed "chocoholic" who has pioneered brain-imaging studies of addiction. Caffeine does activate some of the same brain circuits as the drugs of addiction, but only very mildly, she says. Caffeine can be habit-forming, but Starbucks devotees won’t risk jail time or divorce to feed their habit.

Nor is addiction the same as dependence, although the American Psychiatric Association’s diagnostic manual says it is, says Volkow, who’s pushing to drop that wording. "Addiction is much harder to treat. Everybody given an opiate (such as morphine) will become physically dependent, but not everybody will become an addict."

WorldWideAddiction.com — Substance Addiction has been recognized "officially" as a disease for many years now, but there is still a great deal of ignorance on the subject -even amongst the medical profession.

Addicts/alcoholics (people tend to separate the two, but from here on in I will use the term "addict" to cover the broad range of substance abusers) are seen as weak people with no will-power.

Want to know what will-power is?

It is waking up in the morning, so nauseous that you race to the bathroom and don’t know which end to use first! After that initial wake-up purge, you then make your way shivering and shaking into the kitchen and drink an open, flat, warm beer that has a cigarette butt floating in it. Or because you are shaking so much, you drink that warm white wine that has been sitting out all night, through a straw since you can’t hold a glass! You do this, choking back the bile that is rising in your throat, because you know that the only way to begin functioning again on some sort of level is to try and build up the alcohol in your system before you take a seizure.

Do you think drinking methylated spirits at 5am in the morning is an easy thing to do?

I have known many addicts whose veins in their arms and legs are so damaged, that they inject themselves in their eyeballs. Because going without their "hit" is a far worse option.

Addicts have plenty of will-power…….

…it’s just focused in the wrong direction. Recovery teaches them us to refocus energy.

Back to the disease concept. Addiction is classified as a disease because it meets the criteria of all other terminal diseases:

- It has pattern of symptoms which are similar across all types of substance abuse

- It is a chronic condition. It doesn’t go away.

- It is progressive. Addiction only gets worse with continued use, and ends with death.

- The person is subject to relapse. In Australia, 66% of addicts who are lucky to live long enough to make it to detox will eventually die as a direct result of the disease.

- It is treatable. Here’s the good news, while substance addiction is a terminal illness, its progression can be arrested at almost any stage. But if you are seeking treatment, it is of the utmost importance that you gain medical advice. Sudden withdrawal, even from "socially acceptable" drugs such as alcohol, can cause death through seizures and coma.

It is crucial that you consult with a medical practitioner that understands addiction and withdrawal. Some well meaning, but uneducated doctors will prescribe large amounts of unsuitable medications that can lead to cross-addiction. This happened to me at one stage, and made a difficult situation worse. If you are addicted to one drug, the likelihood of becoming addicted to others is extremely high.

Wherever possible, detoxification is best carried out in a detox unit, where there is 24 hour patient care. There are a number of these units around the world, and in some cases (especially in Australia) there is no charge for this care.

When world governments begin to understand that the cost in providing this care free of charge is far outweighed by the benefits to society, we will begin to see an incredible drop in poverty, violence and divorce. The cost in providing this care will also be offset by the decrease in need of other hospitalization. 1 in 3 hospital beds in Australia are taken up by people with conditions that can be directly linked to drug abuse. At best, the world health systems overall are only currently providing band-aid solutions to one of the greatest scourges of mankind.

Are you thinking of getting help for yourself or a loved one?… do it now … for tomorrow may be too late. 

If you had terminal cancer, would you do anything about it? 

Substance addiction is a far worse disease in my opinion -it not only destroys the person, but everyone around them.

To those who helped me all those years ago -doctors, nurses, friends and strangers – even though I may not have been appreciative at the time….. my sincerest thank you. My life means something now.

Addiction is a disease, not just a state of mind.

WorldWideAddiction.com — Addiction is a very complex subject. The following is short explanation of it.

Substance addiction is a double edged sword. It is a physical compulsion coupled with a mental obsession with the substance being the focus. Because it attacks from these two fronts, it is an extremely hard problem to deal with. The disease is progressive, incurable and fatal, but can be arrested at almost any stage.

There is more and more evidence mounting to suggest that it is a genetic condition, an inherited intolerance. Addiction is a disease that affects around 5% of the worlds’ population. The disease concept I will expand on in another article, as this is a controversial subject.

A person having a genetic predisposition to the disease is usually not aware of it. The threshold between abuse and addiction is invisible and different in all individual sufferers. Some people can be successful social drinkers for years, and then – literally overnight, become alcoholic. Others, like myself, are addicted from the first experience.

The pattern of addiction is this:

- A drug is consumed and creates a desirable effect (not necessarily a high, it may be just a feeling of contentment or oblivion or pain relief)

- The behavior is repeated because of the desired effects

- The brain builds a tolerance to the substance, so it takes more each time to achieve the same effect. As addiction sets in, these original sensations that are pursued are never achieved again.

- The brain becomes "used" to the substance and creates triggers when the substance is not used to turn the persons attention towards it (cravings).

- After a period , the person is spending more time thinking about the drug and therefore retarding mental and emotional growth as these thought patterns become deeply entrenched. Aside from the undesirable effects of the abuse of the drug itself, one of the outcomes of being so preoccupied with the substance is that it prevents healthy relationships from being formed and maintained.

- After a further period of time, the brain also sends out physical indicators when the drug is not being used (sweating, shaking), known as withdrawals. These physical symptoms are caused by a release of chemicals that occurs while the drug is being used, especially in the case of CNS (Central Nervous System) depressants such as alcohol. The drug is depressing the CNS, so the brain counteracts with "stimulants" in an attempt to achieve balance. When the consumption of the drug is suddenly stopped, the brain is continuing to produce these chemicals at high concentrations which effectively send the body and brain into "overload". This overload can present itself in grand mal seizures and can be severe enough to cause death. Alcohol is one of the most dangerous drugs to withdraw from.

- Because the sufferer is caught between the states of either being under the influence, recovering from the last consumption or thinking about the next one, their lives and the lives of all those around them become severely affected. High absenteeism from employment due to intoxication/associated physical illness and the expense of the substance leads to loss of work, social standing, financial security and self esteem. This sparks off a whole series of problems within self and family. If the person is approached by a loved one about the problem, this can create a strong defensive reaction. Lying and deceit now sets in.

If the drug is illegal, usage creates a network of people around the sufferer who are in the same situation to ensure a constant supply. Because substances sometimes cost a great deal of money, the person learns the "tricks of the trade" to procure it – mainly prostitution and theft. What would have at one stage be considered "insanity" by the sufferer, slowly becomes normal as this network of people begins to play a bigger role in their life. 

Because most drugs decrease inhibition and impair areas of the brain which control aggression and memory, incidents occur whilst under the influence which would be considered out of character for the person. As periods of intoxication increase, so do the incidents. As the impairment to these areas of the brain increase, the incidents may become more violent. Once again what was considered "insane" now becomes normal for the person.

The above pattern is repeated many times and becomes ingrained, so even when the usage is totally stopped, many of the thought patterns and coping mechanisms are still there. Ceasing the consumption is not enough, the sufferer needs to learn how to cope mentally and emotionally through life without the substance and how to integrate back into mainstream society again. This can take many years.

Even after long periods of cessation from the substance, the brain remembers it. When the addict begins using again, the downhill slide is very quick. You do not get to start from scratch. Addiction does not disappear. It’s in me….but it sleeps…. I am lucky that recognize I now have a conscious choice whether I wake it or not.

Addiction is not a weak person’s "designer disease". It just makes people weak……

Drug addiction is a treatable disorder. Through treatment that is tailored to individual needs, patients can learn to control their condition and live normal, productive lives. Like people with diabetes or heart disease, people in treatment for drug addiction learn behavioral changes and often take medications as part of their treatment regimen.

Behavioral therapies can include counseling, psychotherapy, support groups, or family therapy. Treatment medications offer help in suppressing the withdrawal syndrome and drug craving and in blocking the effects of drugs. In addition, studies show that treatment for heroin addiction using methadone at an adequate dosage level combined with behavioral therapy reduces death rates and many health problems associated with heroin abuse.

In general, the more treatment given, the better the results. Many patients require other services as well, such as medical and mental health services and HIV prevention services. Patients who stay in treatment longer than 3 months usually have better outcomes than those who stay less time. Patients who go through medically assisted withdrawal to minimize discomfort but do not receive any further treatment, perform about the same in terms of their drug use as those who were never treated. Over the last 25 years, studies have shown that treatment works to reduce drug intake and crimes committed by drug-dependent people. Researchers also have found that drug abusers who have been through treatment are more likely to have jobs.

Types of Treatment Programs

The ultimate goal of all drug abuse treatment is to enable the patient to achieve lasting abstinence, but the immediate goals are to reduce drug use, improve the patient’s ability to function, and minimize the medical and social complications of drug abuse.

There are several types of drug abuse treatment programs. Short-term methods last less than 6 months and include residential therapy, medication therapy, and drug-free outpatient therapy. Longer term treatment may include, for example, methadone maintenance outpatient treatment for opiate addicts and residential therapeutic community treatment.

In maintenance treatment for heroin addicts, people in treatment are given an oral dose of a synthetic opiate, usually methadone hydrochloride or levo-alpha-acetyl methadol (LAAM), administered at a dosage sufficient to block the effects of heroin and yield a stable, noneuphoric state free from physiological craving for opiates. In this stable state, the patient is able to disengage from drug-seeking and related criminal behavior and, with appropriate counseling and social services, become a productive member of his or her community.

Outpatient drug-free treatment does not include medications and encompasses a wide variety of programs for patients who visit a clinic at regular intervals. Most of the programs involve individual or group counseling. Patients entering these programs are abusers of drugs other than opiates or are opiate abusers for whom maintenance therapy is not recommended, such as those who have stable, well-integrated lives and only brief histories of drug dependence.

Therapeutic communities (TCs) are highly structured programs in which patients stay at a residence, typically for 6 to 12 months. Patients in TCs include those with relatively long histories of drug dependence, involvement in serious criminal activities, and seriously impaired social functioning. The focus of the TC is on the resocialization of the patient to a drug-free, crime-free lifestyle.

Short-term residential programs, often referred to as chemical dependency units, are often based on the "Minnesota Model" of treatment for alcoholism. These programs involve a 3- to 6-week inpatient treatment phase followed by extended outpatient therapy or participation in 12-step self-help groups, such as Narcotics Anonymous or Cocaine Anonymous. Chemical dependency programs for drug abuse arose in the private sector in the mid-1980s with insured alcohol/cocaine abusers as their primary patients. Today, as private provider benefits decline, more programs are extending their services to publicly funded patients.

Methadone maintenance programs are usually more successful at retaining clients with opiate dependence than are therapeutic communities, which in turn are more successful than outpatient programs that provide psychotherapy and counseling. Within various methadone programs, those that provide higher doses of methadone (usually a minimum of 60 mg.) have better retention rates. Also, those that provide other services, such as counseling, therapy, and medical care, along with methadone generally get better results than the programs that provide minimal services.

Drug treatment programs in prisons can succeed in preventing patients’ return to criminal behavior, particularly if they are linked to community-based programs that continue treatment when the client leaves prison. Some of the more successful programs have reduced the rearrest rate by one-fourth to one-half. For example, the "Delaware Model," an ongoing study of comprehensive treatment of drug- addicted prison inmates, shows that prison-based treatment including a therapeutic community setting, a work release therapeutic community, and community-based aftercare reduces the probability of rearrest by 57 percent and reduces the likelihood of returning to drug use by 37 percent.

Drug abuse has a great economic impact on society-an estimated $67 billion per year. This figure includes costs related to crime, medical care, drug abuse treatment, social welfare programs, and time lost from work. Treatment of drug abuse can reduce those costs. Studies have shown that from $4 to $7 are saved for every dollar spent on treatment. It costs approximately $3,600 per month to leave a drug abuser untreated in the community, and incarceration costs approximately $3,300 per month. In contrast, methadone maintenance therapy costs about $290 per month.

Cocaine and methamphetamine are two drugs that are often linked together because they produce similar effects and because they belong to the same class of drugs called psychostimulants. In addition, they both have the potential for causing dependence and abuse which further strengthens the bond associate between them. Though there are many similarities, a fair number of differences do also exist, which will be discussed here.
 

Where Do They Come From?
 

Methamphetamine is man made, while cocaine is derived from the coca plant.
 

Is There A Difference in the Way They Are Used?
 

Both can be smoked, injected intravenously or snorted. The difference being that methamphetamine can be taken in pill form. In addition, cocaine can be used medically as an anesthetic and as an appetite stimulant while methamphetamine has no proven medical use.

Where and By Whom Are the Drugs Used?
 

Out of the two drugs, Methamphetamine has a much more defined area of use as well as stereotype of user. Statistics show that use of methamphetamine is highest in western areas of California, Honolulu, Hawaii, and western areas of the continental United States. Urban areas of California, Oregon, Arizona, Colorado and Washington, show increased use of methamphetamines. In recent years however, use of methamphetamine has increased in rural and urban areas of the South and Midwest.
 

Cocaine use varies so there is no geographic pattern that clearly delineates where the drugs are used. Cocaine use however, is usually significantly higher in large cities and metropolitan areas as opposed to non-metropolitan areas.
 

A possible reason for the difference between cocaine and methamphetamine addiction by area is that in rural areas, cocaine is not as easily accessible. Methamphetamine however, can be made in a garage or basement with household products, making it quite easy for individuals to make their own high.
 

Do They Produce The Same Effects?
 

* Perhaps the reason why cocaine and methamphetamines are confused is because both produce a very well received rush almost immediately. This is followed by feelings of extreme happiness or euphoria which is referred to as a rush.
 

* Methamphetamine’s high can last from eight to twenty four hours and fifty percent of the drug is removed from the body in twelve hours. Cocaine’s high on the other hand, lasts from twenty to thirty minutes and fifty percent of the drug is removed from the body in one hour.
 

* Both cocaine and methamphetamine, when injected intravenously or smoked, can cause an almost immediate rush which is followed by a high.
 

* When ingested nasally, which is referred to as snorting, neither methamphetamine nor cocaine cause a rush or a high. A similar effect is produced when methamphetamine is ingested orally.

Are the Physiological Effects Similar?
 

* Both methamphetamine and cocaine can cause immediate effects of irritability, anxiety, increased heart rate, blood pressure, body temperature and possible death. Methamphetamine’s and cocaine’s short-term effects also can include increased activity, respiration, and wakefulness, and decreased appetite.
 

* Chronic use of cocaine or methamphetamine can cause dependence and possibly stroke.
 

* In either case, cocaine or methamphetamine can lead to psychotic behavior. These behaviors are characterized by hallucinations, paranoia, violence, and mood disturbance.
 

* Some data suggests that violence is more common among methamphetamine users than among cocaine users. Drug craving, paranoia, and depression can occur in addicted individuals who try to stop using either methamphetamine or cocaine.
Is there a difference in neurotoxicity?
 

* Neurotoxicity refers to the toxic damage these drugs can incur on the brain, specifically on neuron transmission. Neurons are responsible for the processing and transferring of information. Methamphetamine can be neurotoxic in animal species ranging from mice to monkeys. Methamphetamine specifically damages neurons that produce serotonin and dopamine. Since the usual doses taken by humans are comparable to the doses causing neurotoxicity in animals, it is reasonable to believe that this also causes the same effect in humans.
 

* On the other hand, cocaine does not cause neurotoxic damage to dopamine and serotonin neurons.
 

Transmission of HIV/AIDS
 

Whether discussing methamphetamine or cocaine, a risk for HIV/AIDS still exists and must be considered when engaging in any type of sexual behavior.